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In the present study, anticoagulant and platelet modulating activities of an acidic phospholipase A 2 (NnPLA 2 -I) purified from Indian cobra Naja naja venom was investigated. The NnPLA 2 -I displayed a mass of 15.2 kDa and 14,186.0 Da when analyzed by SDS-PAGE and MALDI-TOF-MS, respectively. Peptide mass fingerprinting analysis of the NnPLA 2 -I showed its significant...
This is the first report on antithrombin effects of a phospholipase A 2 (RVAPLA 2 ) purified from venom of Daboia russelii russelii. The N-terminal sequence as well as in-gel tryptic digested peptides of RVAPLA 2 showed significant homology with PLA 2 s from Russell's viper venom. RVAPLA 2 demonstrated highest specific activity in hydrolyzing phosphatidylcholine...
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