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A highly informative microsatellite marker,D7S485, from the T-cell receptor γ (TCRG) locus, has been used to study segregation ofTCRGgenes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores for theD7S485marker...
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