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Background
Progressive supranuclear palsy (PSP) is difficult to diagnose accurately. The recently developed tau PET tracers may improve the diagnostic work‐up of PSP.
Methods
Regional tau accumulation was studied using 18F‐AV‐1451 PET in 11 patients with PSP and 11 age‐matched healthy controls in the Swedish BioFinder study.
Results
18F‐AV‐1451 standard uptake volume ratios were significantly...
[ 18 F]-(E)-3-((6-Fluoropyridin-2-yl)ethynyl)cyclohex-2-enone O-methyl oxime ([ 18 F]-FPECMO) is a novel derivative of [ 11 C]-ABP688. [ 18 F]-FPECMO was characterized as a PET imaging agent for the metabotropic glutamate receptor subtype 5 (mGluR5).[ 18 F]-FPECMO was synthesized in a one-step reaction sequence by reacting [ 18 F]-KF-K 222 complex...
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