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Although the BRAF V600E base substitution is an approved target for the BRAF inhibitors in melanoma, BRAF gene fusions have not been investigated as anticancer drug targets. In our study, a wide variety of tumors underwent comprehensive genomic profiling for hundreds of known cancer genes using the FoundationOne™ or FoundationOne Heme™ comprehensive genomic profiling assays. BRAF fusions involving...
Aiming at a realization of effective and less invasive cancer screening tests and therapies using Au nanoparticles which tend to aggregate around cancer parts, the distributional region of Au nanoparticles within a scattering medium of agar was detected by applying an image reconstruction method of the ultrasonic velocity change imaging.
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