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Background and Objectives
The ideal duration of neoadjuvant chemotherapy (NACT) in patients with localized pancreatic adenocarcinoma (PDAC) treated with curative intent is unclear. We sought to determine the prognostic significance of both duration of NACT and Carbohydrate Antigen 19‐9 (CA19‐9) normalization to NACT.
Methods
We examined patients with resectable and borderline resectable PDAC treated...
BACKGROUNDMixed lineage kinase domain‐like protein (MLKL) is a necrosome component mediating programmed necrosis that may be an important determinant of cancer cell death. The goal of the current study was to evaluate the prognostic value of MLKL expression in patients with pancreatic adenocarcinoma (PAC).
METHODSTissue from 80 patients was collected from a prospectively maintained database of patients...
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