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The treatment of reperfusion injury after ischemic stroke remains unsatisfactory since the blood‐brain barrier (BBB) prevents most neuroprotective agents from entering the brain. Here, a strategy is proposed based on bacteria‐derived outer‐membrane vesicle (OMV) hitchhiking on the neutrophils for enhanced brain delivery of pioglitazone (PGZ) to treat ischemic stroke. By encapsulating PGZ into OMV,...
Rehabilitation is necessary for the recovery of patients with paralysis caused by stroke and muscle atrophy. Wearable electronics can provide feedback on physical training and facilitate healthcare. However, most existing wearable electronics are difficult to maintain a conformal skin‐device interface. Additionally, the use of non‐degradable electronic materials is associated with environmental risks...
The abnormal pressure in tumor tissue is a significant limitation on the drug delivery efficiency of tumor therapy. This work reports a gradient‐driven nanomotor as drug nanocarrier with the pressure‐counterworking function. The dual‐fuel nanomotors are formed by co‐electrospinning of the photosensitive polymers with calcium peroxide (CaO2) and catalase (CAT), followed by ultraviolet (UV) irradiation...