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Background: Muscle strength declines with advancing age; the causes of this are uncertain. In women; strength begins to decline around the time of menopause, suggesting that hormonal changes might influence strength. To determine the effect of postmenopausal estrogen use on muscle strength, neuromuscular function, and the risk of falling, we examined 9704 participants aged 65 years or more enrolled...
Objective: To assess the association of unopposed estrogen or estrogen plus progestin and the risk of developing endometrial cancer or dying of that disease. Data Sources: A literature search of English-language studies was performed using MEDLINE, a review of bibliographies, and consultations with experts. Methods of Study Selection: We identified 30 studies with adequate controls and risk estimates...
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