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Miltefosine is a phospholipid analog that exhibits antineoplastic activity against breast cancer metastases, but its mechanism of action remains uncertain. The aim of this study was to investigate the transport mechanism for the removal of miltefosine and [ 99m Tc]-hexakis-2-methoxyisobutyl isonitrile ( 99m Tc-MIBI) from multidrug-resistant cells. The P-glycoprotein pump function,...
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