Search results for: Eric D. Peterson

Items from 1 to 20 out of 689 results

article

The HEART Pathway: Just a HEART score permutation or the future of clinical decision rules?

Samuel A. McDonald, Eric D. Peterson

Academic Emergency Medicine > 29 > 8 > 1037 - 1039

article

Weight Can’t Wait: A Guide to Discussing Obesity and Organizing Treatment in the Primary Care Setting

Christine Gallagher, Amelia Corl, William H. Dietz, Bellinda Schoof, more

Obesity > 29 > 5 > 821 - 824

Objective The objective of this study was to develop a simple and practical guide for discussing and managing obesity in primary care settings. Methods This study convened representatives from 12 primary care and obesity specialty organizations for a series of roundtable meetings to discuss the key components of obesity treatment in primary care. Attendees identified the need for a guide for primary...

article

A systematic review of randomized trials comparing double versus triple antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention

Alexander E. Sullivan, Michael G. Nanna, Sunil V. Rao, Sarah Cantrell, more

Catheterization and Cardiovascular Interventions > 96 > 2 > E102 - E109

Background Prior randomized controlled trials (RCT) evaluating the optimal antithrombotic therapies for patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) have not been powered to evaluate ischemic outcomes. We compared double therapy with oral anticoagulation (OAC) and a P2Y12 inhibitor to triple therapy with an OAC + dual antiplatelet therapy in patients...

article

Racial Differences in Elevated C‐Reactive Protein Among US Older Adults

Heather R. Farmer, Linda A. Wray, Ying Xian, Hanzhang Xu, more

Journal of the American Geriatrics Society > 68 > 2 > 362 - 369

OBJECTIVES To investigate racial differences in elevated C‐reactive protein (CRP) and the potential factors contributing to these differences in US older men and women. DESIGN Nationally representative cohort study. SETTING Health and Retirement Study, 2006 to 2014. PARTICIPANTS Noninstitutionalized non‐Hispanic black and white older adults living in the United States (n = 13 517). MEASUREMENTS...

article

The Association Between Low‐Density Lipoprotein Cholesterol and Incident Atherosclerotic Cardiovascular Disease in Older Adults: Results From the National Institutes of Health Pooled Cohorts

Michael G. Nanna, Ann Marie Navar, Daniel Wojdyla, Eric D. Peterson

Journal of the American Geriatrics Society > 67 > 12 > 2560 - 2567

BACKGROUND/OBJECTIVES Elevated low‐density lipoprotein cholesterol (LDL‐C) in early adulthood is associated with increased risk of atherosclerotic cardiovascular disease (ASCVD). The strength of the association between LDL‐C and ASCVD among older adults, however, is less understood. DESIGN We examined individual‐level cohort data from the National Institutes of Health Pooled Cohorts (Framingham...

article

Sitagliptin does not reduce the risk of cardiovascular death or hospitalization for heart failure following myocardial infarction in patients with diabetes: observations from TECOS

Michael A. Nauck, Darren K. McGuire, Karen S. Pieper, Yuliya Lokhnygina, more

Cardiovascular Diabetology > 2019 > 18 > 1 > 1-10

Background To examine the effects of the DPP-4i sitagliptin on CV outcomes during and after incident MI in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS). Methods TECOS randomized 14,671 participants with type 2 diabetes and atherosclerotic cardiovascular disease (ASCVD) to sitagliptin or placebo, in addition to usual care. For those who had a within-trial MI, we analyzed...

article

Sex differences in management and outcomes of patients with type 2 diabetes and cardiovascular disease: A report from TECOS

Joakim Alfredsson, Jennifer B. Green, Susanna R. Stevens, Shelby D. Reed, more

Diabetes, Obesity and Metabolism > 20 > 10 > 2379 - 2388

Aim To examine sex differences in baseline characteristics and outcomes in patients with type 2 diabetes and atherosclerotic vascular disease. Materials and methods Cox models were used to analyse the association between sex and outcomes in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS), a randomized, placebo‐controlled trial assessing the impact of sitagliptin on cardiovascular...

article

Leveraging electronic health records for clinical research

Sudha R. Raman, Lesley H. Curtis, Robert Temple, Tomas Andersson, more

American Heart Journal > 2018 > 202 > C > 13-19

Electronic health records (EHRs) can be a major tool in the quest to decrease costs and timelines of clinical trial research, generate better evidence for clinical decision making, and advance health care. Over the past decade, EHRs have increasingly offered opportunities to speed up, streamline, and enhance clinical research. EHRs offer a wide range of possible uses in clinical trials, including...

article

Early therapeutic persistence on dabigatran versus warfarin therapy in patients with atrial fibrillation: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry

Larry R. Jackson, Sunghee Kim, Peter Shrader, Rosalia Blanco, more

Journal of Thrombosis and Thrombolysis > 2018 > 46 > 4 > 435-439

Anticoagulation is highly effective for the prevention of stroke in patients with atrial fibrillation (AF) but it is dependent on patients continuing therapy. While studies have demonstrated suboptimal therapeutic persistence on warfarin, few have studied persistence rates with non vitamin K antagonist oral anticoagulants (NOACs) such as dabigatran. We examined rates of continued use of dabigatran...

article

Total bleeding with rivaroxaban versus warfarin in patients with atrial fibrillation receiving antiplatelet therapy after percutaneous coronary intervention

Gerald Chi, Megan K. Yee, Arzu Kalayci, Mathieu Kerneis, more

Journal of Thrombosis and Thrombolysis > 2018 > 46 > 3 > 346-350

Among atrial fibrillation (AF) patients undergoing percutaneous coronary intervention (PCI), rivaroxaban with background antiplatelet therapy significantly reduced the first occurrence of bleeding compared to triple therapy with warfarin. This study hypothesized that total bleeding events, including those beyond the first event, would be reduced with rivaroxaban-based regimens. In the PIONEER AF-PCI...

article

Longitudinal medical resources and costs among type 2 diabetes patients participating in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS)

Shelby D. Reed, Yanhong Li, Jose Leal, Larry Radican, more

Diabetes, Obesity and Metabolism > 20 > 7 > 1732 - 1739

Aims TECOS, a cardiovascular safety trial (ClinicalTrials.gov identifier: NCT00790205) involving 14 671 patients with type 2 diabetes and cardiovascular disease, demonstrated that sitagliptin was non‐inferior to placebo for the primary composite cardiovascular outcome when added to best usual care. This study tested hypotheses that medical resource use and costs differed between these 2 treatment...

article

Implantable cardioverter‐defibrillators in heart failure patients with reduced ejection fraction and diabetes

Abhinav Sharma, Sana M. Al‐Khatib, Justin A. Ezekowitz, Lauren B. Cooper, more

European Journal of Heart Failure > 20 > 6 > 1031 - 1038

Aim There is limited information on the outcomes after primary prevention implantable cardioverter‐defibrillator (ICD) implantation in patients with heart failure (HF) and diabetes. This analysis evaluates the effectiveness of a strategy of ICD plus medical therapy vs. medical therapy alone among patients with HF and diabetes. Methods and results A patient‐level combined‐analysis was conducted from...

article

Does clinician-reported lipid guideline adoption translate to guideline-adherent care? An evaluation of the Patient and Provider Assessment of Lipid Management (PALM) registry

Angela Lowenstern, Shuang Li, Ann Marie Navar, Salim Virani, more

American Heart Journal > 2018 > 200 > C > 118-124

The 2013 American College of Cardiology (ACC)/American Heart Association (AHA) cholesterol guideline recommends statin treatment based on patients' predicted atherosclerotic cardiovascular disease (ASCVD) risk. Whether clinician-reported guideline adoption translates to implementation into practice is unknown.We aimed to compare clinician lipid management in hypothetical scenarios versus observed...

article

Effect of race on the glycaemic response to sitagliptin: Insights from the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS)

Timothy M. E. Davis, Hillary Mulder, Yuliya Lokhnygina, Pablo Aschner, more

Diabetes, Obesity and Metabolism > 20 > 6 > 1427 - 1434

Aim Pooled efficacy studies suggest that glycaemic responses to dipeptidyl‐peptidase 4 inhibitors in type 2 diabetes are greatest in Asians, who may also respond better to alpha‐glucosidase inhibitors. We assessed the glycaemic impact of sitagliptin by race in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS), and whether this was enhanced in Asians with concomitant acarbose therapy...

article

External validation of the TIMI risk score for secondary cardiovascular events among patients with recent myocardial infarction

Brent A. Williams, Kevin M. Chagin, Lori D. Bash, William E. Boden, more

Atherosclerosis > 2018 > 272 > C > 80-86

Risk stratification of patients with recent myocardial infarction (MI) for subsequent cardiovascular (CV) events helps identify patients most likely to benefit from secondary prevention therapies. This study externally validated a new risk score (TRS2˚P) for secondary events derived from the TRA2°P-TIMI 50 trial among post-MI patients from two large health care systems.This retrospective cohort study...

article

Improving patient risk communication: Translating cardiovascular risk into standardized risk percentiles

Ann Marie Navar, Michael J. Pencina, Hillary Mulder, Pierre Elias, more

American Heart Journal > 2018 > 198 > C > 18-24

Current cholesterol guidelines recommend using 10-year risk of atherosclerotic cardiovascular disease (ASCVD) to guide informed decisions regarding statin therapy, yet patients may have difficulty conceptualizing absolute risk estimates. Peer comparisons may provide an improved tool for patient risk comprehension.Using data from the 2009–2014 National Health and Nutrition Examination Survey (NHANES),...

article

Hospital evaluation of health literacy and associated outcomes in patients after acute myocardial infarction

Jennifer A. Rymer, Lisa A. Kaltenbach, Kevin J. Anstrom, Gregg C. Fonarow, more

American Heart Journal > 2018 > 198 > C > 97-107

Low health literacy is common in the United States and may affect outcomes after myocardial infarction (MI). How often hospitals screen for low health literacy is unknown.We surveyed 122 hospitals in the TRANSLATE-ACS study and divided them into those that reported routinely (>75% of patients), selectively (1%-75%), or never (0%) screening MI patients for low health literacy prior to discharge...

article

The safety and effectiveness of adenosine diphosphate receptor inhibitor pretreatment among acute myocardial infarction patients treated with percutaneous coronary intervention in community practice: Insights from the TRANSLATE‐ACS study

Mark B. Effron, Tracy Y. Wang, Gregg C. Fonarow, Timothy D. Henry, more

Catheterization and Cardiovascular Interventions > 91 > 2 > 242 - 250

Objectives To understand the optimal timing of adenosine diphosphate (ADP) receptor inhibitor pretreatment prior to percutaneous coronary intervention (PCI) among acute myocardial infarction (MI) patients. Background The role of ADP receptor inhibitor pretreatment in this population is unclear. Methods A total of 9,251 ADP receptor inhibitor‐naïve MI patients undergoing PCI at 229 TRANSLATE‐ACS...

article

Training cardiovascular outcomes researchers: A survey of mentees and mentors to identify critical training gaps and needs

Prateeti Khazanie, Sana M. Al-Khatib, Tracy Y. Wang, Matthew J. Crowley, more

American Heart Journal > 2018 > 196 > C > 170-177

Many young investigators are interested in cardiovascular (CV) outcomes research; however, the current training experience of early investigators across the United States is uncertain.From April to November 2014, we surveyed mentees and mentors of early-stage CV outcomes investigators across the United States. We contacted successful grantees of government agencies, members of professional organizations,...

article

Access to routine care and risks for 30-day readmission in patients with cardiovascular disease

Matthew E. Dupre, Hanzhang Xu, Bradi B. Granger, Scott M. Lynch, more

American Heart Journal > 2018 > 196 > C > 9-17

Studies have shown that access to routine medical care is associated with the prevention, diagnosis, and treatment of chronic diseases. However, studies have not examined whether patient-reported difficulties in access to care are associated with rehospitalization in patients with cardiovascular disease.Electronic medical records and a standardized survey were used to examine cardiovascular patients...

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Keywords

PERCUTANEOUS CORONARY INTERVENTION (25)
MYOCARDIAL INFARCTION (21)
OUTCOMES (19)
HEART FAILURE (16)
ATRIAL FIBRILLATION (13)
GUIDELINES (11)
ACUTE MYOCARDIAL INFARCTION (9)
CORONARY ARTERY DISEASE (8)
ACUTE CORONARY SYNDROMES (7)
ANTIPLATELET THERAPY (7)
QUALITY IMPROVEMENT (7)
ACUTE CORONARY SYNDROME (6)
ANTITHROMBOTIC THERAPY (6)
BLEEDING (6)
MORTALITY (6)
QUALITY INDICATORS (6)
RISK FACTORS (6)
SITAGLIPTIN (6)
STROKE (6)
COMPARATIVE EFFECTIVENESS (5)
DIABETES (5)
REGISTRIES (5)
ACCF/AHA PRACTICE GUIDELINES (4)
CHRONIC KIDNEY DISEASE (4)
CLINICAL TRIALS (4)
CORONARY ARTERY BYPASS GRAFT SURGERY (4)
FOCUSED UPDATE (4)
GLYCOPROTEIN IIB/IIIA INHIBITORS (4)
MEDICARE (4)
PATIENT CARE (4)
PERFORMANCE MEASURES (4)
PROGNOSIS (4)
QUALITY MEASUREMENT (4)
QUALITY OF CARE (4)
REGISTRY (4)
THIENOPYRIDINES (4)
WARFARIN (4)
ACC/AHA PERFORMANCE MEASURES (3)
ACCF/AHA PERFORMANCE MEASURES (3)
ANGIOPLASTY (3)
ANTICOAGULATION (3)
AORTIC STENOSIS (3)
CARDIOGENIC SHOCK (3)
CARDIOVASCULAR DISEASE (3)
CLINICAL RESEARCH (3)
CORONARY DISEASE (3)
NON–ST ELEVATION (3)
RACE (3)
RIVAROXABAN (3)
SECONDARY PREVENTION (3)
THROMBOSIS (3)
UNSTABLE ANGINA (3)
23 (2)
35 (2)
4 (2)
ACC/AHA CLINICAL PRACTICE GUIDELINES (2)
ACCF HEALTH POLICY STATEMENT (2)
AGE (2)
ANGINA, UNSTABLE (2)
ANTICOAGULANT (2)
ANTIPLATELET AGENTS (2)
AORTIC VALVE REPLACEMENT (2)
APIXABAN (2)
BLEEDING RISK (2)
CABG (2)
CARDIAC ARREST (2)
CLINICAL OUTCOMES (2)
COMPARATIVE EFFECTIVENESS RESEARCH (2)
CORONARY ANGIOGRAPHY (2)
CORONARY ARTERY BYPASS GRAFT (2)
DABIGATRAN (2)
DATABASE (2)
DEATH (2)
ELECTROCARDIOGRAPHY (2)
EPIDEMIOLOGY (2)
ETHNICITY (2)
HEALTH CARE POLICY (2)
HEALTH POLICY AND OUTCOME RESEARCH (2)
INSTITUTIONAL VARIABILITY (2)
ISCHEMIA (2)
LENGTH OF STAY (2)
LONG-TERM OUTCOMES (2)
MEDICATION ADHERENCE (2)
NON–ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION (2)
OBESITY (2)
ORAL ANTICOAGULATION (2)
OUTCOMES ANALYSIS (2)
P2Y12 RECEPTOR INHIBITOR (2)
PATIENT SELECTION (2)
PCI (2)
PERFORMANCE MEASUREMENT (2)
PERIOPERATIVE CARE (2)
PERIPHERAL ARTERY DISEASE (2)
PRACTICE OF MEDICINE (2)
PREVENTION (2)
QUALITY MEASURE (2)
QUALITY OF LIFE (2)
RADIONUCLIDE ANGIOGRAPHY (2)
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Journal of the American College of Cardiology (225)
American Heart Journal (202)
The Annals of Thoracic Surgery (59)
The American Journal of Cardiology (51)
The American Journal of Medicine (19)
Journal of Cardiac Failure (18)
JACC: Cardiovascular Interventions (16)
The Journal of Thoracic and Cardiovascular Surgery (12)
Annals of Emergency Medicine (10)
Journal of Thrombosis and Thrombolysis (10)
Diabetes, Obesity and Metabolism (5)
Journal of Stroke and Cerebrovascular Diseases (4)
Catheterization and Cardiovascular Interventions (3)
Global Heart (3)
Journal of General Internal Medicine (3)
Journal of the American Geriatrics Society (3)
Academic Emergency Medicine (2)
European Journal of Cardio-Thoracic Surgery (2)
International Journal of Cardiology (2)
Journal of Cardiovascular Electrophysiology (2)
Journal of Critical Care (2)
Journal of Nuclear Cardiology (2)
Journal of the American College of Surgeons (2)
Resuscitation (2)
Revista Espanola de Cardiologia (English Edition) (2)
ACC Current Journal Review (1)
American Journal of Emergency Medicine (1)
American Journal of Kidney Diseases (1)
Annals of Epidemiology (1)
Archives of Physical Medicine and Rehabilitation (1)
Atherosclerosis (1)
Canadian Journal of Cardiology (1)
Cardiovascular Diabetology (1)
Clinical Cardiology (1)
Clinical Therapeutics (1)
Current Cardiology Reports (1)
European Journal of Heart Failure (1)
JACC: Cardiovascular Imaging (1)
Journal of Cardiac Surgery (1)
Journal of Cardiothoracic and Vascular Anesthesia (1)
Journal of Diabetes and Its Complications (1)
Journal of Medical Systems (1)
Journal of Vascular Nursing (1)
Journal of the American Medical Directors Association (1)
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Obesity (1)
Solar Energy (1)
Solar Energy Materials and Solar Cells (1)
Surgery (1)
Synthetic Metals (1)
The Journal of Rural Health (1)
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INFONA - science communication portal

Search results for: Eric D. Peterson

The HEART Pathway: Just a HEART score permutation or the future of clinical decision rules?

Weight Can’t Wait: A Guide to Discussing Obesity and Organizing Treatment in the Primary Care Setting

A systematic review of randomized trials comparing double versus triple antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention

Racial Differences in Elevated C‐Reactive Protein Among US Older Adults

The Association Between Low‐Density Lipoprotein Cholesterol and Incident Atherosclerotic Cardiovascular Disease in Older Adults: Results From the National Institutes of Health Pooled Cohorts

Sitagliptin does not reduce the risk of cardiovascular death or hospitalization for heart failure following myocardial infarction in patients with diabetes: observations from TECOS

Sex differences in management and outcomes of patients with type 2 diabetes and cardiovascular disease: A report from TECOS

Leveraging electronic health records for clinical research

Early therapeutic persistence on dabigatran versus warfarin therapy in patients with atrial fibrillation: results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry

Total bleeding with rivaroxaban versus warfarin in patients with atrial fibrillation receiving antiplatelet therapy after percutaneous coronary intervention

Longitudinal medical resources and costs among type 2 diabetes patients participating in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS)

Implantable cardioverter‐defibrillators in heart failure patients with reduced ejection fraction and diabetes

Does clinician-reported lipid guideline adoption translate to guideline-adherent care? An evaluation of the Patient and Provider Assessment of Lipid Management (PALM) registry

Effect of race on the glycaemic response to sitagliptin: Insights from the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS)

External validation of the TIMI risk score for secondary cardiovascular events among patients with recent myocardial infarction

Improving patient risk communication: Translating cardiovascular risk into standardized risk percentiles

Hospital evaluation of health literacy and associated outcomes in patients after acute myocardial infarction

The safety and effectiveness of adenosine diphosphate receptor inhibitor pretreatment among acute myocardial infarction patients treated with percutaneous coronary intervention in community practice: Insights from the TRANSLATE‐ACS study

Training cardiovascular outcomes researchers: A survey of mentees and mentors to identify critical training gaps and needs

Access to routine care and risks for 30-day readmission in patients with cardiovascular disease

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