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A simple and highly sensitive high-performance liquid chromatographic (HPLC) method for the simultaneous determination of cis(Z)-clopenthixol and trans(E)-clopenthixol in human plasma has been developed. The chromatographic analysis was carried out isocratically on a reversed-phase column (C 8 150x4.6 mm I.D., 5 μm) using a mixture of 25 mM phosphate buffer and acetonitrile (65:35 v/v, pH*...
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