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This study evaluated the effect of interferon-γ (IFN-γ) upon the function and expression of type 1 Na + /H + exchanger (NHE1) in human intestinal epithelial HT-29 cells, namely that concerning the abundance of surface NHE1 and NHE1 binding to the ezrin, radixin and moesin (ERM) family of proteins. HT-29 cells express endogenous NHE1 and the ERM family of proteins that retain the localization...
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