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ABSTRACTThe study deals with the effect of ethanolic extract of Withania coagulans fruits on normal and streptozotocin‐induced diabetic models. The maximum reduction of 39.2% in fasting blood glucose at 4 h and 39.9% during oral glucose tolerance test at 2 h was observed with the dose of 750 mg/kg in normal rats, whereas the reduction observed was 47.1 and 42.7% in blood glucose levels of sub‐ and mild diabetic rats, respectively, at 2 h during oral glucose tolerance test with the same dose. Long‐term study of severely diabetic rats showed reduction of 48.5 and 52.6% in fasting blood glucose and postprandial glucose levels, respectively, after 30 days of treatment. In addition 75% decrease in urine sugar and 13.08% increase in body weight of treated group was found at the end of the experiment. Trace elements present in the text were identified through laser‐induced breakdown spectroscopy....
ABSTRACTThe present study is an extension of our previous research work and it deals with the scientific evaluation of antioxidant potential of the aqueous extract of Cynodon dactylon on diabetes‐induced oxidative stress of diabetic rats. The most effective dose of 500 mg/kg of extract was given orally to diabetic rats for 30 days. Different oxidative stress parameters were analyzed in various tissues of control and treated diabetic rats. The observed elevated level of LPO comes down significantly (...
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