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Dodecyl‐β‐d‐selenomaltoside (SeDDM) is a seleno‐detergent with a β‐glycosidic seleno‐ether in place of the ether moiety in dodecyl‐β‐d‐maltoside. Seleno‐detergents are candidates for heavy‐atom agents in experimental phasing of membrane proteins in protein crystallography. Crystals of a nuclear membrane‐embedded enzyme, leukotriene C4 synthase (LTC4S), in complex with SeDDM were prepared and a multiwavelength...
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