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Aims/Purpose: Lipoprotein‐associated phospholipase A2 (Lp‐PLA2) activity have been linked to a higher risk of diabetic retinopathy and inhibiting Lp‐PLA2 activity showed improvement in vision and macular oedema for patients with diabetic macular oedema (DME). SR1375 is an orally available, selective inhibitor of Lp‐PLA2 that shows significant retinal vascular leakage reduction in preclinical studies,...
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