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PC12 pheochromocytoma cells have P 2 purinoceptors which are activated by ATP and coupled to Ca 2+ influx and catecholamine release. Also PC12 cells have adenosine receptors coupled positively to adenylyl cyclase, and cyclic AMP regulates cell functions such as catecholamine release. The effects of ATP and ATP analogs on cyclic AMP accumulation in PC12 cells were investigated...
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