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Background
The potential role of circFNDC3B in regulating oral tongue squamous cell carcinoma development (OTSCC) remains unknown.
Methods
The level of circFNDC3B in OTSCC tissues or cell lines was measured and its function in vitro and in vivo was analyzed. Interactions among circFNDC3B, miR‐1322, and MED1 were verified by luciferase reporter and RNA pull‐down assays.
Results
The level of circFNDC3B...
Background
Reconstruction of hemiglossectomy defects requires careful flap design to avoid adverse functional and aesthetic outcomes.
Methods
Hemitongue specimens were obtained from minipigs to study the three‐dimensional anatomy and to define anatomic landmarks for precise measurements of flap requirement. The concept developed in animal models was then applied to hemiglossectomy reconstruction...
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