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Three new polysulfur alkaloids, lissoclibadins 1 (1)–3 (3), were isolated from the ascidian Lissoclinum sp. (cf. L. badium Monniot, F. and Monniot, C., 1996). The structures of 1–3 were assigned on the basis of their spectral data, and the computational modeling study was utilized for 1. Compound 1 had a trimeric structure of three identical aromatic anime moieties connected through two sulfide and...
A novel tribenzotetrathiepin alkaloid, named lissoclibadin 1 (1), has been isolated from the ascidian Lissoclinum sp. (cf. L. badium Monniot and Monniot, 1996). The gross structure was assigned on the basis of the spectral data, and one of two possible isomers was selected by the computational modeling study. Lissoclibadin 1 inhibited the growth of the marine bacterium Ruegeria atlantica (15.2mm at...
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