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Three peptide toxins (Am I–III) with crab toxicity were isolated from the sea anemone Anthopleura maculata by gel filtration and reverse-phase HPLC. Am I was weakly lethal to crabs (LD 50 830μg/kg) and Am III was potently lethal (LD 50 70μg/kg), while Am II was only paralytic (ED 50 420μg/kg). The complete amino acid sequences of the three toxins were determined by cDNA cloning...
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