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An explanation of the preconditioning phenomenon must account for the biology of the phenomenon. Here we provide a more thorough characterization of ischaemic preconditioning (IPC), examining temporal characteristics and the importance of the size of area at risk. IPC was induced by two 10-min LAD occlusions separated by 30 min reperfusion in pentobarbital anaesthetized open-chest pigs. The last brief...
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