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Background
The present study examined the effect of liposomes conjugated with antisense oligonucleotide of nerve growth factor (NGF‐OND) on local overexpression of NGF and bladder overactivity using rats with prostatic inflammation (PI).
Methods
Male Sprague‐Dawley rats were divided into three groups: (1) Control group; intact rats, (2) PI‐NS group; rats with PI and intravesical instillation of...
Key points
There is clinical evidence showing that prostatic inflammation contributes to overactive bladder symptoms in male patients; however, little is known about the underlying mechanisms
In this study, we investigated the mechanism that prostatic inflammation causes detrusor overactivity by using a rat model of chemically induced prostatic inflammation.
We observed a significant number of dorsal...
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