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Purpose of Review Drug-induced liver injury (DILI) is a complex diagnosis dominantly based of exclusion. Recent Findings Currently available causality assessment instruments are considered to be suboptimal. Expert opinion appears to be best method to adjudicate causality, but is impractical to implement on a wide scale basis. Thus, new approaches are needed, for example, improving the specificity...
The diagnosis of drug-induced liver injury relies on exclusion of other causes, including viral hepatitis A, B, and C. Hepatitis E virus (HEV) infection has been proposed as another cause of suspected drug-induced liver disease. We assessed the frequency of HEV infection among patients with drug-induced liver injury in the United States. The Drug-Induced Liver Injury Network (DILIN) is a prospective...
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