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Cardiac Resynchronization Therapy (CRT) can be optimized by the fusion of anatomical, functional and electrical information in a unified framework in order to identify the most effective pacing sites. The aim of this work is to perform a registration between dynamic CT and ultrasound (US) images (2D speckle tracking mode). The proposed registration approach is based on a contour to surface scheme,...
Previous studies have shown that cardiac microacceleration signals, recorded either cutaneously, or embedded into the tip of an endocardial pacing lead, provide meaningful information to characterize the cardiac mechanical function. This information may be useful to personalize and optimize the cardiac resynchronization therapy, delivered by a biventricular pacemaker, for patients suffering from chronic...
In this work, we sought to assist the optimization of Cardiac Resynchronization Therapy (CRT) through the characterization of electro-mechanical delays for each region of the Left Ventricle. This characterization is based on the fusion of electrical, mechanical and anatomical data acquired from Electro-Anatomical Mapping (EAM), Speckle Tracking Echocardiography (STE) and Multislice CT (MSCT) imaging,...
The goal of this work is to evaluate the capabilities of Multislice Computed Tomography (MSCT) to assess local cardiac function. MSCT dynamic acquisition provides datasets representing the whole cardiac cycle, enabling to describe the left ventricle both anatomically and functionally. In order to estimate the cardiac function, a motion estimation method has been proposed, based on a multi-resolution...
Heart sounds, measured via cardiac micro-acceleration (CMA), carry valuable information about the mechanical and hemodynamic function of the heart. The aim of the present study is to estimate systolic and diastolic time intervals from CMA features, extracted by segmentation of the first two heart sounds, i.e. onset, maximum energy and end instants. CMA, ECG and echocardiographic audio signals were...
New tools for the assessment of intra-ventricular dyssynchrony can enable the optimization of Bi-ventricular cardiac resynchronization therapy. Multislice-CT (MSCT) imaging may be a good complement to ultrasound (US) imaging modalities. Moreover, its potential to get a functional and anatomical description of the heart within a single exam constitutes a motivation for this work. This paper is focused...
This paper presents a model-based method for the analysis of regional myocardial strain, based on echocardiography and Tissue Doppler Imaging (TDI). A multi- formalism, tissue-level electromechanical model of the left ventricle is proposed. The parameters of the model are identified in order to reproduce regional strain signal morphologies obtained from a healthy subject and a patient presenting a...
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