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Dynamic, ECG-gated, steady-state free precession short-axis images were obtained (GE Healthcare, 1.5T) in 8-12 slices in 15 patients with previous myocardial infarction. An expert cardiologist provided the reference values for: 1) left ventricular (LV) volumes and mass, by manually tracing endo and epicardial contours; 2) regional wall motion (WM) interpretation, by grading (normal, abnormal) three...
The quantitative evaluation of the morphology of the mitral annulus (MA) could have a great impact in both diagnosis and surgical treatment of mitral valve diseases. In this study we aimed at creating a framework for the 3D reconstruction of the MA from CMR cine images. The developed tool allowed the measurement of several geometric parameters relevant to the MA and the papillary muscles in the 3D...
Management of heart failure is challenging for all healthcare systems, due to the need of several expensive imaging examinations and image analysis procedures to address different clinical questions. In particular, a correct identification of transmural extent of irreversible myocardial damage is cost effective, identifying subjects who will most benefit of coronary revascularization. This study show...
Harmonic phase (HARP) is an image processing technique of MR-tagged images in frequency domain developed to evaluate the regional tissue strain. The filtering stage is a key point in this method because all information about the deformation have to be included in the analysis. In this paper we develop an automatic method to define the filter parameters in order to minimize errors in the strain evaluation...
Cardiovascular magnetic resonance is able to detect myocardial fibrosis by delayed enhancement of a contrast media. However, detection and quantification of fibrosis is difficult due to the complex pattern of the fibrotic tissue signal. In this study a software model of the signal distribution in normal and fibrotic myocardium was inferred from MR images of healthy subjects and patients with hypertrophic...
Assessment of iron overload in liver by T2* magnetic resonance imaging (MRI) is a widely used clinical procedure. In the common clinical practice, measurement is performed locally by manually drawing a small region of interest in liver. This procedure may be affected by a noticeable intra- and inter-observer variability. In this study, a new approach is proposed that performs a global semi-automatic...
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