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Anti‐Tumor Immunity
An “ABC” ternary membrane‐derived nanosystem blended from antigen‐presenting mature dendritic cell membranes (“A”), bacterial E. coli cytoplasmic membranes (“B”), and cancer cell membranes (“C”), shows great promise for use as a personalized tumor nanovaccine. ABC nanovaccine elicits immune responses on patient‐derived dendritic cells (DCs) by homologous vaccines and promotes recovery...
Cancer vaccines generally are limited by insufficient tumor‐specific cellular immunogenicity. Herein, a potent “ABC” ternary membrane‐derived vaccine system blended from antigen‐presenting mature dendritic cell membranes (“A”), bacterial E. coli cytoplasmic membranes (“B”), and cancer cell membranes (“C”) is developed using a block‐copolymer micelle‐enabled approach. The respective ABC membrane components...
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