Search results for: Furong Gao

Items from 1 to 20 out of 193 results

article

A comprehensive stem cell laboratory module with blended learning for medical students at Tongji University

Jie Xu, Zhihua Shao, Song Jia, Jihong Sha, more

Biochemistry and Molecular Biology Education > 52 > 3 > 291 - 298

The laboratory practice “Primary culture and directional differentiation of rat bone marrow mesenchymal stem cells (BMSCs)” is part of a required course for sophomore medical students at Tongji university, which has been conducted since 2012. Blended learning has been widely applied in medical courses. Based on a student‐centered teaching philosophy, we reconstructed a comprehensive stem cell laboratory...

article

GMFB/AKT/TGF‐β3 in Müller cells mediated early retinal degeneration in a streptozotocin‐induced rat diabetes model

Tong Zhu, Yingao Li, Lilin Zhu, Jinyuan Xu, more

Glia > 72 > 3 > 504 - 528

Retinal degeneration, characterized by Müller cell gliosis and photoreceptor apoptosis, is considered an early event in diabetic retinopathy (DR). Our previous study proposed that GMFB may mediate diabetic retinal degeneration. This study identified GMFB as a sensitive and functional gliosis marker for DR. Compared to the wild type (WT) group, Gmfb knockout (KO) significantly improved visual function,...

article

Effect of acid‐activation on CaO existential state and reactive properties of hot‐splashed steel slag in cement‐based materials

Yangmei Zhou, Yongsheng Ji, Zhongzhe Zhang, Zhanguo Ma, more

Structural Concrete > 23 > 6 > 3819 - 3833

The over‐burnt free‐CaO(f‐CaO) existential state in hot‐splashed steel slag is understood by observing the microstructure of steel slag section and analyzing the minerals in the steel slag (SS). In the investigation, a new method of using hydrochloric acid as the solvent to modify the steel slag powder (SSP) is put forward. The effects of hydrochloric acid pretreatment on the surface morphology of...

article

Improving early compressive strength of precast concrete by increasing active silicon content

Zhongzhe Zhang, Yongsheng Ji, Zhanguo Ma, Ou Geng, more

Structural Concrete > 23 > 6 > 3995 - 4009

In order to make the precast concrete reach the design strength quickly, by increasing the active silicon content of the precast concrete, the influence mechanism of the active silicon on the early compressive strength of the precast concrete was studied. The early hydration process, early pore structure, and chemical composition of precast concrete mixed with different types and dosages of water‐soluble...

article

Optimal synchronization control for heterogeneous multi‐agent systems: Online adaptive learning solutions

Yuanqiang Zhou, Dewei Li, Furong Gao

Asian Journal of Control > 24 > 5 > 2352 - 2362

This paper presents an online adaptive learning solution to the optimal synchronization control problem of heterogeneous multi‐agent systems via a novel distributed policy iteration approach. For the leader‐follower multi‐agents, the dynamics of all the followers are heterogeneous with leader disturbance. To make the output of each follower synchronize with the leader's output, we propose a synchronization...

article

Improvement effect of a phase change material on microstructure of cement‐based materials at elevated temperatures

Furong Gao, Linglei Zhang, Yongsheng Ji, Yan Gao, more

Structural Concrete > 23 > 4 > 2233 - 2245

In this investigation, a phase change material with a melting temperature of about 450°C (PCM‐45) is prepared and applied to solve microstructure degradation problem of concrete matrix when exposed to temperatures more than 500°C. The morphology changes of PCM‐45 and the improvement effects of PCM‐45 on microstructure of cement matrix are investigated based on microstructure characteristics, ultrasonic...

article

Identification of novel key molecular signatures in the pathogenesis of experimental diabetic retinopathy

Caiying Liu, Tong Zhu, Jieping Zhang, Juan Wang, more

IUBMB Life > 73 > 11 > 1307 - 1324

Deep mining of the molecular mechanisms underlying diabetic retinopathy (DR) is critical for the development of novel therapeutic targets. This study aimed to identify key molecular signatures involved in experimental DR on the basis of integrated bioinformatics analysis. Four datasets consisting of 37 retinal samples were downloaded from the National Center of Biotechnology Information Gene Expression...

article

Literature‐based learning and experimental design model in molecular biology teaching for medical students at Tongji University

Juan Wang, Xiaojuan Xu, Xiujuan Shi, Jieping Zhang, more

Biochemistry and Molecular Biology Education > 49 > 2 > 189 - 197

In 2018, to help undergraduate medical students strengthen their self‐learning and scientific research skills, we introduced an instructional model that combined literature‐based learning with experimental design. We tested this model on the molecular biology class at Tongji University. In the first step of the model, a topic is chosen, and students find, read, and evaluate scientific papers in groups...

article

Gradation effect of cleaned quarry waste to improve size distributions of concrete constituents

Furong Gao, Yongsheng Ji, Qi Xue, Zhishan Xu, more

Structural Concrete > 22 > S1 > E245 - E256

A specially designed cleaning system was adopted to wash away mud but keep coarse particles and stone powders in quarry waste. Then the cleaned quarry waste was used as concrete fine aggregate. Size distributions of all concrete constituents were analyzed, and workability and compressive strength of concrete were determined to evaluate gradation effect of cleaned quarry waste to improve size distributions...

article

Separation of mononuclear cells and identification of B lymphocytes: A comprehensive experiment for medical students

Jiao Li, Furong Gao, Caixia Jin, Xiujuan Shi, more

Biochemistry and Molecular Biology Education > 48 > 3 > 283 - 290

In teaching of experiments for medical students, by using the isolation of mononuclear cells and identification of B lymphocytes, an experiment was developed that integrated biochemistry, cytology, and immunology techniques, from which the students performed a series of operations including spleen separation, isolating mononuclear cells, and identifying B lymphocytes. From the immunocytochemistry...

article

Erythropoietin protects outer blood‐retinal barrier in experimental diabetic retinopathy by up‐regulating ZO‐1 and occludin

Chaoyang Zhang, Hai Xie, Qian Yang, Yiting Yang, more

Clinical & Experimental Ophthalmology > 47 > 9 > 1182 - 1197

Purpose To explore the mechanisms of erythropoietin (EPO) in maintaining outer blood‐retinal barrier (BRB) in diabetic rats. Methods Sprague‐Dawley rats were rendered diabetic with intraperitoneal injection of streptozotocin, and then followed by intravitreal injection of EPO. Two and four weeks later, the permeability of outer BRB was examined with FITC‐dextran leakage assay, following a method...

article

Evaluating the appropriateness of AccessMedicine in integrated biochemistry learning for chinese medical students

Furong Gao, Jiao Li, Jie Xu, Song Jia, more

Biochemistry and Molecular Biology Education > 47 > 3 > 272 - 278

Recently, Chinese medical education has exhibited a shifting trend from teacher‐centered instruction to student‐centered learning, which usually includes a self‐directed learning process. Providing students with high‐quality and appropriate supplemental resources is necessary for their self‐directed learning. This study aimed to investigate the appropriateness of AccessMedicine, an online medical...

article

The combination of bFGF and CHIR99021 maintains stable self-renewal of mouse adult retinal progenitor cells

Caixia Jin, Qingjian Ou, Zongyi Li, Juan Wang, more

Stem Cell Research & Therapy > 2018 > 9 > 1 > 1-12

Background Millions of people are affected with retinal diseases that eventually cause blindness, and retinal progenitor cell (RPC) transplantation is a promising therapeutic avenue. However, RPC expansion and the underlying regulation mechanisms remain elusive. Methods Adult mouse neural RPCs (mNRPCs) were isolated and amplified with the combination of basic fibroblast growth factor (bFGF) and...

article

Guaranteed Cost Iterative Learning Control for Multi-Phase Batch Processes

Limin Wang, Runze Wang, Yuting Xiong, Haosen Wang, more

Journal of Shanghai Jiaotong University (Science) > 2018 > 23 > 6 > 811-819

Batch process is a typical multi-phase process. Due to the interaction between the phases of the batch process, high precision control in a single phase cannot guarantee high precision control of the whole batch process. In order to solve this problem, the guaranteed cost iterative learning control (ILC) of multi-phase batch processes is studied in this paper. Firstly, through introducing the output...

article

Design of fuzzy iterative learning fault‐tolerant control for batch processes with time‐varying delays

Limin Wang, Bingyun Li, Jingxian Yu, Ridong Zhang, more

Optimal Control Applications and Methods > 39 > 6 > 1887 - 1903

In this paper, a new two‐dimensional (2D) fuzzy composite iterative learning fault‐tolerant control strategy using a 2D Takagi‐Sugeno fuzzy model is proposed for batch processes with time delay and actuator faults. Firstly, based on the local‐sector nonlinearity method, a 2D Takagi‐Sugeno fuzzy model representing the nonlinear batch process with actuator faults is constructed with a series of linear...

article

A fast estimation algorithm for lithium-ion battery state of health

Xiaopeng Tang, Changfu Zou, Ke Yao, Guohua Chen, more

Journal of Power Sources > 2018 > 396 > C > 453-458

This paper proposes a novel and computationally efficient estimation algorithm for lithium-ion battery state of health (SoH) under the hood of incremental capacity analysis. Concepts of regional capacity and regional voltage are introduced to develop an SoH model against experimental cycling data from four types of batteries. In the obtained models, SoH is a simple linear function of the regional...

article

Pseudomonas aeruginosa infection alters the macrophage phenotype switching process during wound healing in diabetic mice

Sinuo Chen, Renren Li, Chun Cheng, Jing‐Ying Xu, more

Cell Biology International > 42 > 7 > 877 - 889

Macrophages play critical roles in wound healing process. They switch from “classically activated” (M1) phenotype in the early inflammatory phase to “alternatively activated” (M2) phenotype in the later healing phase. However, the dynamic process of macrophage phenotype switching in diabetic wounds burdened with bacteria is unclear. In this report, Pseudomonas aeruginosa, frequently detected in diabetic...

article

Inner-phase and inter-phase analysis based operating performance assessment and nonoptimal cause identification for multiphase batch processes

Yan Liu, Ruicheng Ma, Fuli Wang, Yuqing Chang, more

Chemical Engineering Research and Design > 2018 > 134 > C > 292-308

Batch processes play a significant role in modern industrial processes. Nevertheless, the process operating performance may degrade from optimal level, which cancels the economic profits of the plant, and effective techniques for operating performance assessment are essential. Although multimodel approaches are proposed to fit its multiphase characteristic, the effect of combined action of multiple...

article

Linearity Evaluation and Variable Subset Partition Based Hierarchical Process Modeling and Monitoring

Wenqing Li, Chunhui Zhao, Furong Gao

IEEE Transactions on Industrial Electronics > 2018 > 65 > 3 > 2683 - 2692

Complex industrial processes may be formulated with hybrid correlations, indicating that linear and nonlinear relationships simultaneously exist among process variables, which brings great challenges for process monitoring. However, previous work did not consider the hybrid correlations and treated all the variables as a single subject in which single linear or nonlinear analysis method was employed...

article

An automatic glucose monitoring signal denoising method with noise level estimation and responsive filter updating

Hong Zhao, Chunhui Zhao, Furong Gao

Biomedical Signal Processing and Control > 2018 > 41 > C > 172-185

Although continuous glucose monitoring (CGM) devices have been the crucial part of the artificial pancreas, their success has been discounted by random measurement noise. The difficulty of denoising methods for CGM is that the filter parameters are hard to be determined to well reflect the internal blood glucose dynamics and the real noise level. Besides, the noise level may change from device to...

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INFONA - science communication portal

Search results for: Furong Gao

A comprehensive stem cell laboratory module with blended learning for medical students at Tongji University

GMFB/AKT/TGF‐β3 in Müller cells mediated early retinal degeneration in a streptozotocin‐induced rat diabetes model

Effect of acid‐activation on CaO existential state and reactive properties of hot‐splashed steel slag in cement‐based materials

Improving early compressive strength of precast concrete by increasing active silicon content

Optimal synchronization control for heterogeneous multi‐agent systems: Online adaptive learning solutions

Improvement effect of a phase change material on microstructure of cement‐based materials at elevated temperatures

Identification of novel key molecular signatures in the pathogenesis of experimental diabetic retinopathy

Literature‐based learning and experimental design model in molecular biology teaching for medical students at Tongji University

Gradation effect of cleaned quarry waste to improve size distributions of concrete constituents

Separation of mononuclear cells and identification of B lymphocytes: A comprehensive experiment for medical students

Erythropoietin protects outer blood‐retinal barrier in experimental diabetic retinopathy by up‐regulating ZO‐1 and occludin

Evaluating the appropriateness of AccessMedicine in integrated biochemistry learning for chinese medical students

The combination of bFGF and CHIR99021 maintains stable self-renewal of mouse adult retinal progenitor cells

Guaranteed Cost Iterative Learning Control for Multi-Phase Batch Processes

Design of fuzzy iterative learning fault‐tolerant control for batch processes with time‐varying delays

A fast estimation algorithm for lithium-ion battery state of health

Pseudomonas aeruginosa infection alters the macrophage phenotype switching process during wound healing in diabetic mice

Inner-phase and inter-phase analysis based operating performance assessment and nonoptimal cause identification for multiphase batch processes

Linearity Evaluation and Variable Subset Partition Based Hierarchical Process Modeling and Monitoring

An automatic glucose monitoring signal denoising method with noise level estimation and responsive filter updating

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