Yue-Yu Hu

artykuł

Ginkgolide B Reduces Neuronal Cell Apoptosis in the Traumatic Rat Brain: Possible Involvement of Toll‐like Receptor 4 and Nuclear Factor Kappa B Pathway

Wen‐Hua Yu, Xiao‐Qiao Dong, Yue‐Yu Hu, Man Huang, więcej

Phytotherapy Research > 26 > 12 > 1838 - 1844

Ginkgolide B (GB) has been demonstrated to have a variety of pharmacological actions. Accumulating evidence indicates that GB may exert a protective effect on brain injury. The study was designed to investigate the influence of GB on toll‐like receptor 4 (TLR‐4) and nuclear factor κB (NF‐κB)‐dependent inflammatory responses and neuronal cell apoptosis after traumatic brain injury (TBI). Wistar rats...

artykuł

The protective role of oxymatrine on neuronal cell apoptosis in the hemorrhagic rat brain

Man Huang, Yue-Yu Hu, Xiao-Qiao Dong, Qiu-Ping Xu, więcej

Journal of Ethnopharmacology > 2012 > 143 > 1 > 228-235

Oxymatrine is extracted from the traditional Chinese herb Sophora flavescens Ait, possesses anti-inflammatory, anti-oxidative and anti-apoptotic properties, and has been used for the treatment of chronic viral hepatitis and many other diseases.This study aimed to investigate the effects of oxymatrine on inflammatory response mediated by Toll-like receptor4 (TLR4) and nuclear factor kappa-B (NF-κB),...

artykuł

Ginkgolide B reduces neuronal cell apoptosis in the hemorrhagic rat brain: Possible involvement of Toll-like receptor 4/nuclear factor-kappa B pathway

Yue-Yu Hu, Man Huang, Xiao-Qiao Dong, Qiu-Ping Xu, więcej

Journal of Ethnopharmacology > 2011 > 137 > 3 > 1462-1468

Ginkgolide B (GB) is one of the ginkgolides that have been isolated from leaves and root bark of the Chinese tree Ginkgo biloba L. (Ginkgoaceae), and is a specific and potent antagonist of platelet activating factor. There is a large body of data showing that GB possesses a markedly neuroprotective property against ischemia-induced impairment in vivo and in vitro. Recently it has been found that GB...

artykuł

Oxymatrine reduces neuronal cell apoptosis by inhibiting Toll-like receptor 4/nuclear factor kappa-B-dependent inflammatory responses in traumatic rat brain injury

Xiao-Qiao Dong, Wen-Hua Yu, Yue-Yu Hu, Zu-Yong Zhang, więcej

Inflammation Research > 2011 > 60 > 6 > 533-539

Objective To investigate the influence of oxymatrine (OMT) on Toll-like receptor 4 (TLR-4)/nuclear factor kappa-B (NF-κB)-dependent inflammatory responses and neuronal cell apoptosis after traumatic brain injury (TBI). Materials and methods Wistar rats were given an intraperitoneal injection of 60 or 120 mg/kg OMT after TBI once a day till day 5. Rats were killed by decapitation at hours 2, 6 and...

artykuł

Time Course of Plasma Leptin Concentrations After Acute Spontaneous Basal Ganglia Hemorrhage

Xiao-Qiao Dong, Man Huang, Yue-Yu Hu, Wen-Hua Yu, więcej

World Neurosurgery > 2010 > 74 > 2-3 > 286-293

Brain cortex leptin messenger riboneucleic acid (mRNA) expression and serum leptin level are up-regulated in ischemic mouse brain, as well as in rat brain with traumatic brain injury. Elevated leptin plasma levels predict cerebral hemorrhagic stroke independently of traditional risk factors. The goal of this study was to investigate change in plasma leptin level after intracerebral hemorrhage (ICH)...

artykuł

High concentrations of resistin in the peripheral blood of patients with acute basal ganglia hemorrhage are associated with poor outcome

Xiao-Qiao Dong, Yue-Yu Hu, Wen-Hua Yu, Zu-Yong Zhang

Journal of Critical Care > 2010 > 25 > 2 > 243-247

Resistin increases in peripheral blood of patients with intracerebral hemorrhage (ICH). We sought to evaluate its relation with disease outcome.Thirty healthy controls and 86 patients with acute ICH were included. Plasma samples were obtained on admission. Its concentration was measured by enzyme-linked immunosorbent assay.Thirty-two patients (37.2%) died from ICH in a week. The plasma resistin level...

artykuł

High concentrations of procoagulant microparticles in the cerebrospinal fluid and peripheral blood of patients with acute basal ganglia hemorrhage are associated with poor outcome

Man Huang, Yue-Yu Hu, Xiao-Qiao Dong

Surgical Neurology > 2009 > 72 > 5 > 481-489

Apoptosis plays an important role in further brain injury after intracerebral hemorrhage (ICH). Procoagulant microparticles (MPs) are shed from the plasma membrane of apoptotic cells. The objective of this study was to determine plasma and cerebrospinal fluid (CSF) levels of MPs in patients with spontaneous ICH and to correlate MP levels with Glasgow Coma Scale (GCS) scores, ICH volumes, presence...

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Wyniki wyszukiwania dla: Yue-Yu Hu

Ginkgolide B Reduces Neuronal Cell Apoptosis in the Traumatic Rat Brain: Possible Involvement of Toll‐like Receptor 4 and Nuclear Factor Kappa B Pathway

The protective role of oxymatrine on neuronal cell apoptosis in the hemorrhagic rat brain

Ginkgolide B reduces neuronal cell apoptosis in the hemorrhagic rat brain: Possible involvement of Toll-like receptor 4/nuclear factor-kappa B pathway

Oxymatrine reduces neuronal cell apoptosis by inhibiting Toll-like receptor 4/nuclear factor kappa-B-dependent inflammatory responses in traumatic rat brain injury

Time Course of Plasma Leptin Concentrations After Acute Spontaneous Basal Ganglia Hemorrhage

High concentrations of resistin in the peripheral blood of patients with acute basal ganglia hemorrhage are associated with poor outcome

High concentrations of procoagulant microparticles in the cerebrospinal fluid and peripheral blood of patients with acute basal ganglia hemorrhage are associated with poor outcome

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INFONA - portal komunikacji naukowej

Wyniki wyszukiwania dla: Yue-Yu Hu

Ginkgolide B Reduces Neuronal Cell Apoptosis in the Traumatic Rat Brain: Possible Involvement of Toll‐like Receptor 4 and Nuclear Factor Kappa B Pathway

The protective role of oxymatrine on neuronal cell apoptosis in the hemorrhagic rat brain

Ginkgolide B reduces neuronal cell apoptosis in the hemorrhagic rat brain: Possible involvement of Toll-like receptor 4/nuclear factor-kappa B pathway

Oxymatrine reduces neuronal cell apoptosis by inhibiting Toll-like receptor 4/nuclear factor kappa-B-dependent inflammatory responses in traumatic rat brain injury

Time Course of Plasma Leptin Concentrations After Acute Spontaneous Basal Ganglia Hemorrhage

High concentrations of resistin in the peripheral blood of patients with acute basal ganglia hemorrhage are associated with poor outcome

High concentrations of procoagulant microparticles in the cerebrospinal fluid and peripheral blood of patients with acute basal ganglia hemorrhage are associated with poor outcome

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