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This article examines the effectiveness of using a mathematical model to improve motion estimates from an inertial measurement unit (IMU). Our custom built IMU (termed WIMOTIONZ) is capable of measuring acceleration, angular rate, and the magnetic field vector in three axes. A magnetometer calibration technique that removes external magnetic disturbances is discussed, and the objective function used...
This article compares two techniques for estimating the parameters describing the motion of a phantom designed to investigate shaking baby syndrome. Parameters of a simple computational model and an impulse response function for a linear second order system were both fitted using kinematic measurements of the motion of an inverted jointed pendulum. From the two methods respectively, the rotational...
The aim of this study was to compare the mode of action of the commonly used BK inhibitor paxilline with that of the more recently discovered lolitrem B. Similarities and differences in characteristics of inhibition between the two compounds were investigated. We have previously shown that lolitrem B does not affect the BK channel G–V, in contrast to the rightward shift produced by paxilline. These...
A short convergent synthesis of the fungal metabolites cephalosporolides E and F is reported. The key step makes use of a chelation-controlled Mukaiyama aldol reaction to access the key acyclic spiroacetal precursor with the required syn stereochemistry.
The hierarchical structure of 95 self-reported impulsivity items, along with delay–discount rates for money, was examined. A large sample of college students participated in the study (N=407). Items represented every previously proposed dimension of self-reported impulsivity. Exploratory PCA yielded at least seven interpretable components: Prepared/Careful, Impetuous, Divertible, Thrill and Risk Seeking,...
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