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Chemotherapy for brain glioma has been of limited value due to the inability of transport of drug across the blood-brain barrier (BBB) and poor penetration of drug into the tumor. For overcoming these hurdles, the dual-targeting daunorubicin liposomes were developed by conjugating with p-aminophenyl-α-D-manno-pyranoside (MAN) and transferrin (TF) for transporting drug across the BBB and then targeting...
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