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Thrombotic diseases have a high rate of mortality and disability, and pose a serious threat to global public health. Currently, most thrombolytic drugs especially protein drugs have a short blood‐circulation time, resulting in low thrombolytic efficiency. Therefore, a platelet membrane (Pm) cloaked nanotube (NT‐RGD/Pm) biomimetic delivery system with enhanced thrombolytic efficiency is designed. Nanotubes...
Platelet Membrane Cloaked Nanotubes
In article number 2205260, Fazheng Ren, Yuan Li, and co‐workers developed nature‐inspired platelet membrane‐cloaked nanotubes conjugated with targeting arginine glycine‐aspartic peptide and thrombolytic agent urokinase to achieve clot‐targeting and penetrating. This biomimetic carrier showed a promising effect in improving the thrombolytic efficiency in vitro and...
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