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Objective
We analyzed long‐term changes of lobar glucose metabolic abnormalities in relation to clinical seizure variables and development in a large group of children with medically refractory epilepsy.
Methods
Forty‐one children (25 males) with drug‐resistant epilepsy had a baseline positron emission tomography (PET) scan at a median age of 4.7 years; the scans were repeated after a median of...
Objective
Thalamic injury has been implicated in the development of continuous spike‐wave during slow‐wave sleep (CSWS) in children with epilepsy. We studied thalamic abnormalities in children with CSWS using F‐18‐fluorodeoxyglucose (FDG)–positron emission tomography (PET) imaging.
Methods
Twenty‐three patients (12 male; mean age 9 years) with CSWS and normal thalami on brain magnetic resonance...
Objective
We reviewed our experience of surgery for epileptic spasms (ES) with or without history of infantile spasms.
Methods
Data were reviewed from 65 (33 male) patients with ES who underwent surgery between 1993 and 2014; palliative cases were excluded.
Results
Mean age at surgery was 5.1 (range 0.2–19) years, with mean postsurgical follow‐up of 45.3 (6–120) months. Mean number of anticonvulsants...
ObjectiveCortical resections in epilepsy surgery tend to be larger in children, compared to adults, partly due to underlying pathology. Some children show unilateral multifocal seizure onsets involving much of the hemisphere. If there were a significant hemiparesis present, hemispherectomy would be the procedure of choice. Otherwise, it is preferable to spare the primary sensorimotor cortex. We report...
Purpose: Interictal increase of 11C‐alpha‐methyl‐l‐tryptophan (AMT) on positron emission tomography (PET) can be seen in cortical epileptic foci, and is particularly common in cortical developmental malformations. Therefore, in the present study, we evaluated the clinical and histopathologic correlates of AMT‐PET abnormalities in children with intractable epilepsy undergoing resective surgery.
Methods: ...
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