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The biological properties mediated by the main envelope glycoprotein (GP1) of a mouse-attenuated mutant of Junin virus, named CI67, were investigated in comparison with its parental strain XJCI3, in contrast to the parental strain, this mutant was unable to multiply in primary cultures of mouse embryo fibroblasts (MEFs). Impairment of CI67 multiplication was associated with a lack of virus binding...
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