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The expressions of type I and type II collagen genes were studied by in situ hybridisation in an experimental model of leg-lengthening. Mid-tibial osteotomies were performed on NZW rabbits and stabilised with external fixators. One week later, distraction at a rate of either 0.3 or 1.3 mm/day was started and proceeded until the length of the tibia was increased by 20%. The distraction zones were...
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