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Electroformation and electrofusion of giant vesicles with diameters of 10–20μm have been performed in a microfluidic device with high-density microelectrodes forming the sidewalls of the microchannel. Electroformation of giant vesicles by a solution mixture of phosphatidylcholine (PC) and cholesterol (Chol) with different concentrations under AC electric field was investigated. Under the conditions...
Transdermal drug delivery is a promising approach that allows controlled release of drug over time while avoiding possible degradation due to the gastrointestinal tract or first-pass liver effect. Of many different methods have been employed in transdermal drug delivery, microneedle is a widely explored MEMS-based device that can conveniently penetrate the skin and thus create micrometer-scale openings...
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