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Background In this study, we evaluated if PITX2 DNA methylation is a marker for disease recurrence in lymph node-negative (LNN), steroid hormone receptor-positive (HR+) breast cancer patients. In addition, we studied the association between PITX2 DNA methylation and PITX2 gene expression. Patients and methodsPITX2 DNA-methylation was measured in tumor tissue from 412 LNN/HR+ breast cancer patients...
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