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BACKGROUND
Prostate‐specific antigen (PSA) screening and concomitant treatment can be implemented in several ways. The authors investigated how the net benefit of PSA screening varies between common practice versus “good practice.”
METHODS
Microsimulation screening analysis (MISCAN) was used to evaluate the effect on quality‐adjusted life‐years (QALYs) if 4 recommendations were followed: limited...
Metastatic disease is a major morbidity of prostate cancer (PCa). Its prevention is an important goal.To assess the effect of screening for PCa on the incidence of metastatic disease in a randomized trial.Data were available for 76 813 men aged 55–69 yr coming from four centers of the European Randomized Study of Screening for Prostate Cancer (ERSPC). The presence of metastatic disease was evaluated...
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