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Mitochondria DNA (mtDNA) plays an important role in both aging-associated degenerative diseases and cancers. In this study, a new microfluidic system integrating functional components including a mtDNA extraction module, a polymerase chain reaction (PCR) module and a micro-capillary electrophoresis (MCE) module has been developed. A new approach to vertically integrate these three modules has been...
This paper presents a new platform capable of manipulating a single DNA molecule based on optically-induced dielectrophoretic (ODEP) forces. The ends of lambda-phage DNA were bound with polystyrene beads which can be manipulated by optical images generated by a digital projector. The manipulation process of fluorescent-labeled DNA was observed in real time under the ODEP operation. Two kinds of DNA...
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