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Insulin secretion from pancreatic islet β‐cells is stimulated by glucose. Glucose‐induced insulin release is potentiated or suppressed by hormones and neural substances. Ghrelin, an acylated 28‐amino acid peptide, was isolated from the stomach in 1999 as the endogenous ligand for the growth hormone (GH) secretagogue‐receptor (GHS‐R). Circulating ghrelin is produced predominantly in the stomach and...
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