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Target‐protein‐based pesticide screening has attracted wide‐ranging attention on pesticide science. Pedunsaponin A (PA) is a compound isolated from the root of Pueraria peduncularis, and it has a strong toxic effect on Pomacea canaliculata. Previous studies found that Advlin (PcAdv) and neural Wiskott–Aldrich syndrome isoform X1(PcnWAS) are target proteins of PA when interacted with P. canaliculata...
BACKGROUND
Based on previous research indicating that pedunsaponin A (PA) can destroy the gills of Pomacea canaliculata, we chose the gill as the main research object, and identified the target protein of PA in the gills of P. canaliculata through proteomics and RNA interference (RNAi).
RESULTS
Proteomics showed that 180 proteins were downregulated after PA treatment in P. canaliculata. Among them,...
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