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Background
A randomized phase 3 study was performed to investigate the efficacy and safety of maintenance therapy with S‐1 after induction therapy with carboplatin plus S‐1 in patients with advanced squamous non–small cell lung cancer (NSCLC).
Methods
Chemotherapy‐naive patients with advanced or relapsed squamous NSCLC were treated with carboplatin (area under the curve of 5 on day 1 every 3 weeks)...
Transformation to small cell lung cancer is one phenomenon of acquired resistance to anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors in ALK rearrangement‐positive non‐small cell lung cancer (NSCLC). Few case reports have focused on other types of histological transformation. We report a case of transformation of ALK rearrangement‐positive adenocarcinoma to NSCLC with neuroendocrine differentiation...
Background and objective
Endobronchial ultrasonography with a guide sheath transbronchial biopsy (EBUS‐GS TBB) has been used to diagnose peripheral pulmonary lesions (PPLs). In this study, we evaluated the diagnostic utility of conventional TBB after EBUS‐GS TBB.
Methods
A retrospective analysis of patients who underwent conventional TBB after EBUS‐GS TBB for PPL between August 1, 2012 and December...
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