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In this study, non-fixed red blood cells (RBCs) were coated with a polymeric shell via the layer-by-layer (LbL) self-assembly technique for their potential application in medical blood transfusion. The polymeric shell is achieved through the alternate adsorption of two oppositely charged polymers; chitosan-graft-phosphorylcholine (CH-PC) and alginate (ALG). The process of film formation was followed...
A hybrid, nanosized, localized and release-controlled bone morphogenetic protein delivery system consisting of a liposomal core incorporated into a shell of alternating layer-by-layer self-assembled natural polyelectrolytes has been formulated. Hydrophilic, monodisperse, spherical and stable cationic nanoparticles with an extended shelf-life allowing immediate protein loading prior to clinical administration...
Early and effective diagnosis of sepsis is made possible with the detection of specific biomarkers. This requires the design of a specific and sensitive immunoassay biointerface. In this proceeding, we discussed the modelling and implementation of a novel surface plasmon resonance (SPR) interface featuring nano-gratings and selective surface biochemical functionalization. Simulation suggests that...
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