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This study demonstrated a chitosan (CS)/polyglutamate (PG) polyelectrolyte complex (PEC) hydrogel combined with spherical hydroxyapatite (HAp) particles as an injectable dermal filler for soft-tissue augmentation. The CS/PG PEC hydrogel with oppositely charged ionic cross-linking, a high gel content, and low degradation rate was introduced as a carrier to achieve high shape and volume stability. An...
In this study, the chitosan–polyglutamate hydrogel was developed as injectable polyelectrolyte complex (PEC) scaffold for bone regeneration. In practice, oppositely charged polyelectrolytes were mixed using a static injection mixer, the gelation time was less than 1min. The resorbable PEC scaffold can be in situ-formed as a scaffold for osteoblast ingrowth. The canine alveolar defect model was used...
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