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Buprenorphine plasma concentrations were measured after administering buprenorphine (20μg/kg) into the lumbosacral epidural space of conscious cats chronically instrumented with an epidural catheter. Blood was collected from a jugular vein before injection and 15, 30, 45 and 60min and 2, 3, 4, 5, 6, 8, 12 and 24h after administration. Plasma buprenorphine concentrations were measured using ELISA....
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