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Hoher Widerstand: Mithilfe einer effizienten Methode zum Aufbau N‐methylierter Isopeptidbindungen wurden stabile ubiquitinierte Peptide und Proteine hergestellt, die widerstandsfähig gegen Desubiquitinasen sind (DUBs; siehe Schema). So konnte das Verhalten mehrerer stabiler Ubiquitinkonjugate mit verschiedenen DUBs in vitro und in zellulärer Umgebung studiert werden.
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