Search results for: Chih-Jung Chen

Items from 1 to 20 out of 154 results

article

Cost‐effectiveness analysis of cell‐based versus egg‐based quadrivalent influenza vaccines in the pediatric population in Taiwan

Chia‐Yu Chi, Ming‐Fang Cheng, Karam Ko, Joaquin F. Mould, more

Journal of Medical Virology > 96 > 1 > n/a - n/a

Cell‐based influenza vaccines avoid egg‐adaptive mutations, potentially improving vaccine effectiveness. We assessed the one‐season cost‐effectiveness of cell‐based quadrivalent influenza vaccine (QIVc) against that of egg‐derived quadrivalent influenza vaccines (QIVe) in children (6 months to 17 years of age) from payer and societal perspectives in Taiwan using an age‐stratified static model. Base...

article

Mucinous cystadenocarcinoma of the breast harbours TRPS1 expressions and PIK3CA alterations

Wei‐Yu Chen, Yu‐Hsuan Hu, Yu‐Hsin Tsai, Jen‐Fan Hang, more

Histopathology > 84 > 3 > 550 - 555

Aims Breast mucinous cystadenocarcinoma (BMCA) is a rare tumour recently recognised as a distinct entity by the World Health Organisation Tumour Classification Series. BMCA is a triple‐negative tumour that lacks specific immunohistochemical markers; therefore, distinguishing it from mimickers such as ovarian and pancreatic cystadenocarcinomas requires careful clinicopathological correlation. Due...

article

P‐65: Strategic Realization of the Highest Possible Pixel Density for Quantum Dot Color Converter with Optimized Performance

Chih-Jung Chen, Kuan-An Chen, Wei-Hung Kuo, Chun-I Wu, more

SID Symposium Digest of Technical Papers > 54 > 1 > 1725 - 1727

The light extraction efficiency of QDCC (quantum dot color converter) is low when its aspect ratio (width to thickness ratio) of a subpixel is less than two, which causes the problem in their high‐resolution applications. Using QDPR (quantum dot photoresist) of high OD (optical density) values and PenTile subpixel arrangement, an apparent high‐resolution application is feasible, in which the QDCC...

article

The diagnostic utility of trichorhinophalangeal syndrome type 1 immunohistochemistry for metastatic breast carcinoma in effusion cytology specimens

Chih‐Jung Chen, Jen‐Fan Hang, Yun‐An Chen, Shu‐Jiuan Lin, more

Cancer Cytopathology > 131 > 4 > 226 - 233

Background Trichorhinophalangeal syndrome type 1 (TRPS1) is a novel immunohistochemical marker with excellent performance in distinguishing breast carcinoma from other cancers in surgical specimens. The aim of this study was to evaluate the diagnostic utility of TRPS1 compared with GATA3 for metastatic breast carcinoma in effusion cytology specimens. Methods In total, 91 cell blocks of malignant...

article

Successful treatment of COVID‐associated fungal infection due to Scopulariopsis and Aspergillus in a girl with acute lymphoblastic leukemia

Shih‐Hsiang Chen, Tsung‐Yen Chang, Chen‐Yen Kuo, Chih‐Chen Chang, more

Pediatric Blood & Cancer > 70 > 5 > n/a - n/a

article

Dataset for pathology reporting of ductal carcinoma in situ, variants of lobular carcinoma in situ and low‐grade lesions: recommendations from the International Collaboration on Cancer Reporting (ICCR)

Stephen B Fox, Fleur Webster, Chih‐Jung Chen, Boon Chua, more

Histopathology > 81 > 4 > 467 - 476

Aims To describe a new international dataset for pathology reporting of ductal carcinoma in situ (DCIS), variants of lobular carcinoma in situ (LCIS) and low‐grade lesions (encapsulated papillary carcinoma, solid papillary carcinoma in situ, Paget's disease) produced by the International Collaboration on Cancer Reporting (ICCR). Methods and results The ICCR, a global alliance of pathology bodies,...

article

19‐3: Crucial Effect of Aspect Ratio of Quantum‐Dot Color‐Conversion Pixels on the Performance of High‐Resolution Full‐Color MicroLED Microdisplays

Chih-Jung Chen, Kuan-An Chen, Wei-Hung Kuo, Chun-I Wu, more

SID Symposium Digest of Technical Papers > 53 > 1 > 206 - 209

The light extraction efficiency of the QDCC‐based microLED displays is strong related to the aspect ratio (width/thickness) of the patterned QDCC pixels, because the very thin QDCC films and BM banks are required for the realization of high‐resolution microdisplays for AR and VR applications. We formulate high resolution QD photoresist, which can achieve color gamut higher than 85% BT. 2020 coverage...

article

62‐1: High‐Resolution Quantum‐Dot Photoresist for Full‐Color µ‐LED Microdisplays

Chih-Jung Chen, Kuan-An Chen, Ray-Kuang Chiang

SID Symposium Digest of Technical Papers > 52 > 1 > 884 - 887

Thick‐shell quantum dots (QDs) with high mass absorption of 450 nm blue light (absorbance >1.5 for green QD and absorbance > 2.0 for red QD at concentration of 1 mg QD/1 mL solvent) have been adopted to formulate high resolution QD photoresist (QDPR), which can achieve color gamut higher than 90% BT.2020 coverage at film feature resolution of 5 µm and thickness less than 2 µm. The thermal stability...

article

Combination treatment of Src inhibitor Saracatinib with GMI, a Ganoderma microsporum immunomodulatory protein, induce synthetic lethality via autophagy and apoptosis in lung cancer cells

Ling‐Yen Chiu, I‐Lun Hsin, Jen‐Ning Tsai, Chih‐Jung Chen, more

Journal of Cellular Physiology > 236 > 2 > 1148 - 1157

Saracatinib is an oral Src‐kinase inhibitor and has been studied in preclinical models and clinical trials of cancer therapy. GMI, a fungal immunomodulatory protein from Ganoderma microsporum, possesses antitumor capacity. The aim of this study is to evaluate the cytotoxic effect of combination treatment with saracatinib and GMI on parental and pemetrexed‐resistant lung cancer cells. Cotreatment with...

article

P‐89: Ink Formulation and Film Photo‐Stability of Quantum Dot Color Converters for MicroLED Applications

Chih-Jung Chen, Tsung-Hsing Chiang, Chiao-Yang Lin, Ray-Kuang Chiang

SID Symposium Digest of Technical Papers > 51 > 1 > 1703 - 1706

Both solvent‐based and solvent‐free quantum dots (QDs) polymer nanocomposites were considered for the color converter applications on microLEDs. In the case of patterning QD converters based on inkjet printing, the viscosity and surface tension of inks are required to be less than 12 cps and less than 33 dyne/cm, respectively. The QD color conversion layers (QDCCLs) with thickness of < 10 μm, optical...

article

Calcifying fibrous tumour: An IgG4‐related disease or not?

Yu‐Hsuan Hu, Chen‐Tang Yu, Chih‐Jung Chen, Mei‐Chin Wen

International Journal of Experimental Pathology > 101 > 1-2 > 38 - 44

Calcifying fibrous tumour (CFT) has some of the histopathological features, such as abundant plasma cells and stromal fibrosis, that are exhibited by IgG4‐related diseases (IgG4‐RD). The possible role of IgG4‐positive plasma cells in calcifying fibrous tumour was investigated. The aim of this study was to determine any potential relationship between IgG4‐RD and CFT. Thirteen cases with a total of...

article

Protective effects of galangin against H₂O₂‐induced aging via the IGF‐1 signaling pathway in human dermal fibroblasts

Su‐Ying Wen, Jia‐Yi Chen, Chih‐Jung Chen, Chih‐Yang Huang, more

Environmental Toxicology > 35 > 2 > 115 - 123

Galangin, a natural flavonol, has anti‐inflammatory and antioxidative potential. However, the cytoprotective effects of galangin against oxidative‐induced aging in human fibroblasts have not been well studied. IGF‐1 signaling pathway is associated with the control of aging and longevity in human. The goal of this study was to investigate the effects of galangin on human skin fibroblast HS68 cells...

article

Genomic characterisation of breast fibroepithelial lesions in an international cohort

Nur Diyana Md Nasir, Cedric Chuan Young Ng, Vikneswari Rajasegaran, Suet Far Wong, more

The Journal of Pathology > 249 > 4 > 447 - 460

Fibroepithelial lesions (FELs) are a heterogeneous group of tumours comprising fibroadenomas (FAs) and phyllodes tumours (PTs). Here we used a 16‐gene panel that was previously discovered to be implicated in pathogenesis and progression, to characterise a large international cohort of FELs via targeted sequencing. The study comprised 303 (38%) FAs and 493 (62%) PTs which were contributed by the International...

article

Population structure and transmission modes of indigenous typhoid in Taiwan

Kai-Yu Wang, De-Jen Lee, Shian-Sen Shie, Chih-Jung Chen

BMC Medical Genomics > 2019 > 12 > 1 > 1-8

Background Indigenous typhoid fever was continuing to be identified in Taiwan which has not been endemic for the enteric fever for more than 20 years. The source and transmission by which the local patients acquired typhoid and the population structure of the indigenous typhoid strains remain not well characterized. Methods During 2001 and 2014, non-duplicated clinical Salmonella enterica serovar...

article

Long noncoding RNA HOTAIR promotes invasion of breast cancer cells through chondroitin sulfotransferase CHST15

Liang‐Chih Liu, Yuan‐Liang Wang, Pei‐Le Lin, Xiang Zhang, more

International Journal of Cancer > 145 > 9 > 2478 - 2487

The long noncoding RNA HOTAIR plays significant roles in promoting cancer metastasis. However, how it conveys an invasive advantage in cancer cells is not clear. Here we identify the chondroitin sulfotransferase CHST15 (GalNAc4S‐6ST) as a novel HOX transcript antisense intergenic RNA (HOTAIR) target gene using RNA profiling and show that CHST15 is required for HOTAIR‐mediated invasiveness in breast...

article

Monthly tegafur–uracil maintenance for increasing relapse-free survival in ypStage III rectal cancer patients after preoperative radiotherapy, radical resection, and 12 postoperative chemotherapy cycles: a retrospective study

Yi-Hung Kuo, Chia-Hsuan Lai, Cheng-Yi Huang, Chih-Jung Chen, more

BMC Cancer > 2019 > 19 > 1 > 1-11

Background Current advancements in neoadjuvant therapy and total mesorectal excision have engendered increased local control. However, the survival benefit of preoperative radiotherapy (RT; 5 × 5 Gy) in rectal cancer patients remains inadequate, primarily because of systemic recurrence. In this retrospective single-center study, the effects of monthly tegafur–uracil maintenance (≥6 cycles) after 12...

article

P‐115: Patternable and Ultra‐Thin Quantum Dot Color Conversion Layer for Mini‐Sized White Light LED Backlight

Chih-Jung Chen, Jiun-Yi Lien, Ray-Kuang Chiang

SID Symposium Digest of Technical Papers > 50 > 1 > 1681 - 1684

Thinner, lighter, and cost‐effective white light mini‐LED (WLED) backlight package were developed via microfabrication of the quantum dot‐photoresist (QDPR) film onto the blue flip‐chip LEDs. By mixing green and red giant QDs with negative photoresist for QDPR used in the photolithography process, QD‐polymer films as thin as 4 µm with the light conversion efficiency as high as 55% can be reached....

article

Molecular characteristics and clinical features of pediatric methicillin-susceptible Staphylococcus aureus infection in a medical center in northern Taiwan

Yu-Jen Chen, Po-An Chen, Chih-Jung Chen, Yhu-Chering Huang

BMC Infectious Diseases > 2019 > 19 > 1 > 1-9

Background There have been no reports regarding clinical features and molecular characteristics of childhood methicillin-susceptible Staphylococcus aureus (MSSA) infections in Taiwan. Methods We prospectively collected clinical S. aureus isolates from patients aged < 18 years in a university-affiliated hospital in 2015. Only the first isolate from each patient was included. Medical records were...

article

Naringenin inhibited migration and invasion of glioblastoma cells through multiple mechanisms

Yen‐Yu Chen, Yuh‐Ming Chang, Kuan‐Yi Wang, Pei‐Ni Chen, more

Environmental Toxicology > 34 > 3 > 233 - 239

Glioblastoma (GBM) is the most mortality brain cancer in the world. Due to high invasion and drug resistance cause the poor prognosis of GBM. Naringenin, an ingredient of citrus, exhibits many cellular functions such as antioxidant, anti‐inflammation, and anticancer. Naringenin inhibits the migration of bladder and lung cancer via modulation of MMP‐2 and/or MMP‐9 activities, Naringenin inhibits migration...

article

A microvenular hemangioma with a rare expression of progesterone receptor immunocreativity and a review of the literature

Yi‐Chen Juan, Chih‐Jung Chen, Cheng‐Hsiang Hsiao, Tsu‐Man Chiu

Journal of Cutaneous Pathology > 45 > 11 > 847 - 850

Microvenular hemangioma (MVH) is a rare benign vascular tumor with a controversial etiology, but hormone receptor alterations might be involved. We report a case of MVH in a 41‐year‐old Taiwanese woman who presented with a 1.5 × 1 cm violaceous plaque on left thigh that had appeared 1 year previously. She had taken oral contraceptives for several years and stopped 1 year prior to presentation. Histologically,...

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INFONA - science communication portal

Search results for: Chih-Jung Chen

Cost‐effectiveness analysis of cell‐based versus egg‐based quadrivalent influenza vaccines in the pediatric population in Taiwan

Mucinous cystadenocarcinoma of the breast harbours TRPS1 expressions and PIK3CA alterations

P‐65: Strategic Realization of the Highest Possible Pixel Density for Quantum Dot Color Converter with Optimized Performance

The diagnostic utility of trichorhinophalangeal syndrome type 1 immunohistochemistry for metastatic breast carcinoma in effusion cytology specimens

Successful treatment of COVID‐associated fungal infection due to Scopulariopsis and Aspergillus in a girl with acute lymphoblastic leukemia

Dataset for pathology reporting of ductal carcinoma in situ, variants of lobular carcinoma in situ and low‐grade lesions: recommendations from the International Collaboration on Cancer Reporting (ICCR)

19‐3: Crucial Effect of Aspect Ratio of Quantum‐Dot Color‐Conversion Pixels on the Performance of High‐Resolution Full‐Color MicroLED Microdisplays

62‐1: High‐Resolution Quantum‐Dot Photoresist for Full‐Color µ‐LED Microdisplays

Combination treatment of Src inhibitor Saracatinib with GMI, a Ganoderma microsporum immunomodulatory protein, induce synthetic lethality via autophagy and apoptosis in lung cancer cells

P‐89: Ink Formulation and Film Photo‐Stability of Quantum Dot Color Converters for MicroLED Applications

Calcifying fibrous tumour: An IgG4‐related disease or not?

Protective effects of galangin against H₂O₂‐induced aging via the IGF‐1 signaling pathway in human dermal fibroblasts

Genomic characterisation of breast fibroepithelial lesions in an international cohort

Population structure and transmission modes of indigenous typhoid in Taiwan

Long noncoding RNA HOTAIR promotes invasion of breast cancer cells through chondroitin sulfotransferase CHST15

Monthly tegafur–uracil maintenance for increasing relapse-free survival in ypStage III rectal cancer patients after preoperative radiotherapy, radical resection, and 12 postoperative chemotherapy cycles: a retrospective study

P‐115: Patternable and Ultra‐Thin Quantum Dot Color Conversion Layer for Mini‐Sized White Light LED Backlight

Molecular characteristics and clinical features of pediatric methicillin-susceptible Staphylococcus aureus infection in a medical center in northern Taiwan

Naringenin inhibited migration and invasion of glioblastoma cells through multiple mechanisms

A microvenular hemangioma with a rare expression of progesterone receptor immunocreativity and a review of the literature

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