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Methods were developed to determine amikacin and urea in bronchial epithelial lining fluid of neonates. Urea was determined as ammonium by capillary electrophoresis in combination with capacitively coupled contactless conductivity detection (CE-C4D). The ammonium was produced by enzymatic conversion of urea with urease enzyme. The background electrolyte (BGE) contained 30 mM malic acid, adjusted to...
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