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BackgroundThe purpose of our study was to investigate the anticancer effect of sorafenib on mucoepidermoid carcinoma (MEC) and find its new molecular mechanism.
MethodsThe apoptotic effects of sorafenib were performed using MTS assay, diamidino‐phenylindole (DAPI) staining, Western blotting, reverse transcription‐polymerase chain reaction (RT‐PCR), siRNA, and xenograft.
ResultsSorafenib had apoptotic...
BackgroundThe association of vascular invasion with tumor aggressiveness and poor prognosis in follicular thyroid carcinoma (FTC) remains controversial.
MethodsWe reviewed medical records of 204 patients with histologically confirmed FTC.
ResultsThe disease‐specific survival rates at 5 and 10 years were 94% and 85%, respectively. Using Cox proportional hazard model, the extent of invasiveness and...
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