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Corin is a serine protease that activates atrial natriuretic peptide (ANP). CORIN gene variants have been reported in patients with hypertension. To date, however, the prevalence of CORIN variants in hypertensive patients remains unknown. To understand the prevalence and functional significance of CORIN variants in hypertension, we sequenced CORIN exons in 300 normal and 401 hypertensive individuals...
On the cover: This cover image, by Yue Zhang et al., is based on the Research Article Identification and functional analysis of CORIN variants in hypertensive patients, Pages 1700–1710. DOI: 10.1002/humu.23318.
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