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We previously reported lymphocyte expression of genes encoding enzymes required for steroid metabolism; however, only 17β-HSD and 5α-reductase showed significant enzyme activity. We now investigate regulation of lymphocyte expression for genes encoding 17β-HSD and 5α-reductase. Cultured human T and B lymphoid cell lines and peripheral blood mononuclear cells were treated with known regulators of steroidogenic...
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