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Two novel 16-membered tetraene marcolides, bafilomycins N (1) and O (2), along with two known analogues, JBIR-100 (3) and bafilomycin K (4) were produced from isolate GIC10-1, a Streptomyces sp. strain that was originally cloned from bacterial communities associated with marine sponge Theonella sp. The structures of new bafilomycins 1 and 2 were established by using spectroscopic methods and comparing...
Seven new alkaloids, kuroshines C–G (1–5), 3β-hydroxyzoanthenamide (6), 7α-hydroxyzoanthenamide (7), along with a known compound, zoanthenamine (8), were isolated from the ethanolic extract of Formosan zoanthid Zoanthus kuroshio. Kuroshines C–G (1–5) are alkaloids possess a densely functionalized ring system on the basis of the zoanthamine framework, and compounds 6 and 7 may be categorized as zoanthenamide...
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