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Melastatin-like transient receptor potential 2 (TRPM2) channel is a redox sensitive Ca 2+ -permeable cation channel that can be gated by H 2 O 2 binding to the channel's enzymatic Nudix domain. Since the mechanisms that lead to TRPM2 action in response to H 2 O 2 are not understood, we examined the effects of various antioxidants on H 2 O 2 -induced...
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